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Yes. That is also a terrible idea. Worse than off-brand uses of other medications, because it is addictive on top of being unproven.


I was about to post roughly this comment, but then I remembered reading https://www.gwern.net/Nicotine a while ago:

> many asso⁣ci⁣a⁣tions with harm are con⁣founded by past or present to⁣bacco use [...] but when pure nicotine is ex⁣am⁣ined [...] the harms ap⁣peared min⁣i⁣mal: like all stim⁣u⁣lants, nico⁣tine may raise blood pres⁣sure some⁣what, and is ad⁣dic⁣tive to some de⁣gree, but the risks do not ap⁣pear much more strik⁣ingly harm⁣ful than caffeine [...] There is lit⁣tle ev⁣i⁣dence from the NRT [nicotine replacement therapy] lit⁣er⁣a⁣ture that ‘never-smokers’ like my⁣self are all that likely to be⁣come highly ad⁣dicted

(To be clear, I understand why the medical community would be hesitant to endorse this without it rising to the level of a "cover-up," but it seems like it's not as bad an idea as it intuitively sounds. But it's also unclear if the stimulant levels mentioned in that article are anywhere close to the levels relevant for covid.)


Yet it is strictly necessary in order to test the physical model.


Tobacco addiction stems from psychoactive ”nicotine boosters” both preexisting in the tobacco plant as well as intentionally added to commercial cigarettes. Pure nicotine is not significantly habit-forming by itself. Just don’t combine it with coffee.


Then why do nicotine gums and patches work?


Desperation. Acetyl aldéhydes in tobacco are highly addictive. Nicotine supplements do not supply these, but folks manage to quit tobacco using them because they are motivated, and they are the best available alternative.


That’s like asking why amphetamines help speedball freaks quit opiates.




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